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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKA
All Species:
23.33
Human Site:
S650
Identified Species:
46.67
UniProt:
P23743
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23743
NP_001336.2
735
82630
S650
K
T
C
V
P
D
L
S
D
K
R
L
E
V
V
Chimpanzee
Pan troglodytes
XP_001169813
623
69890
E543
D
L
S
D
K
R
L
E
V
V
G
L
E
G
A
Rhesus Macaque
Macaca mulatta
XP_001112326
735
82508
S650
K
T
C
V
P
D
L
S
D
K
R
L
E
V
V
Dog
Lupus familis
XP_531626
735
82556
T650
K
T
C
V
P
D
L
T
D
K
R
L
E
V
V
Cat
Felis silvestris
Mouse
Mus musculus
O88673
730
82744
S645
K
T
C
V
P
D
M
S
D
K
R
L
E
V
V
Rat
Rattus norvegicus
P51556
727
82180
S642
K
T
C
V
P
D
M
S
D
K
R
L
E
V
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235516
802
90547
D710
F
V
C
Q
D
L
S
D
Q
L
M
E
V
V
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001038780
727
81728
S647
K
V
S
P
Q
D
M
S
D
K
R
L
E
V
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
V1114
S
A
T
S
F
N
S
V
D
L
S
V
A
I
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
E708
D
I
G
D
G
L
I
E
L
V
G
L
E
S
A
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
S1132
N
R
E
R
D
G
D
S
H
S
T
V
G
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
S637
G
K
L
Q
V
G
L
S
R
A
R
R
L
A
Q
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.6
98.9
92.9
N.A.
82.3
82.7
N.A.
N.A.
57.2
N.A.
62
N.A.
34.7
N.A.
46.1
35.3
Protein Similarity:
100
84.6
99.3
97
N.A.
88.9
88.9
N.A.
N.A.
70
N.A.
74.5
N.A.
44.9
N.A.
62.1
45.1
P-Site Identity:
100
20
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
N.A.
66.6
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
20
100
100
N.A.
100
100
N.A.
N.A.
13.3
N.A.
73.3
N.A.
26.6
N.A.
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
0
0
0
0
0
9
0
0
9
9
17
% A
% Cys:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
17
17
50
9
9
59
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
17
0
0
0
9
67
0
0
% E
% Phe:
9
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
9
0
9
17
0
0
0
0
17
0
9
9
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% I
% Lys:
50
9
0
0
9
0
0
0
0
50
0
0
0
0
0
% K
% Leu:
0
9
9
0
0
17
42
0
9
17
0
67
9
9
0
% L
% Met:
0
0
0
0
0
0
25
0
0
0
9
0
0
0
0
% M
% Asn:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
42
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
17
9
0
0
0
9
0
0
0
0
0
17
% Q
% Arg:
0
9
0
9
0
9
0
0
9
0
59
9
0
0
0
% R
% Ser:
9
0
17
9
0
0
17
59
0
9
9
0
0
9
0
% S
% Thr:
0
42
9
0
0
0
0
9
0
0
9
0
0
0
9
% T
% Val:
0
17
0
42
9
0
0
9
9
17
0
17
9
59
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _